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Ritonavir or lopinavir/ritonavir drastically boost plasma concentrations of oxycodone in wholesome human volunteers as a consequence of inhibition of CYP3A4 and CYP2D6.[58] Rifampicin greatly lowers plasma concentrations of oxycodone on account of strong induction of CYP3A4.Take this medication particularly as prescribed to reduced the chance of de

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